WebPseudoephedrine. The magnitude of risk of seizure for various categories and individual agents is not well established. Factors that may contribute to the risk of seizure with medications include overdose, alcohol abuse, organ dysfunction, drug interactions, older … WebMay 1, 2024 · Lower Seizure Threshold: Promethazine may lower seizure threshold. It should be used with caution in persons with seizure disorders or in persons who are using concomitant medications, such as narcotics …
brompheniramine/dextromethorphan/phenylephrine
WebJan 23, 2024 · Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. Potentiation of anticonvulsant effects does not occur. However, it has been reported that phenothiazines may interfere with the metabolism of Dilantin ®‡ (phenytoin) and thus precipitate Dilantin (phenytoin) toxicity. WebPhenylephrine in an average dose of 0.3 mg/kg after oral administration causes a weak and unreliable anticonvulsant effect, since it eliminates clonic-tonic seizures in only 40% of rats and reduces the average severity of PTZ-induced seizures by 28% (Table 3). Phenylephrine in a high dose of 1 mg/kg, like diazepam, causes a reliable ... ft myers traffic cameras
Pseudoephedrine vs. phenylephrine: Comparison, effects, and more
WebJul 6, 2024 · Many factors often combine to lower the patient's seizure threshold, leading to status epilepticus. Ideally, all factors should be addressed, reducing the likelihood of … Webbrompheniramine increases toxicity of amifampridine by Other (see comment). Modify Therapy/Monitor Closely. Comment: Amifampridine can cause seizures. Coadministration with drugs that lower seizure threshold may increase this risk. amitriptyline. amitriptyline increases and phenylephrine decreases sedation. Effect of interaction is not clear ... WebOct 30, 2024 · Promethazine may lower seizure threshold. This should be taken into consideration when administering to persons with known seizure disorders or when giving in combination with narcotics or local anesthetics which may also affect seizure threshold. Sedative drugs or CNS depressants should be avoided in patients with a history of sleep … gilberton pa is in what county