WebNov 11, 2024 · By Dr. Nicola Williams, Ph.D. Reviewed by Emily Henderson, B.Sc. Emotional dysregulation refers to difficulty in managing emotions or in keeping them in check. These may also be thought of as... Web1 day ago · Senescence is a state of indefinite cell cycle arrest associated with aging, cancer, and age-related diseases. Here, using label-based mass spectrometry, ribosome profiling and nanopore direct RNA sequencing, we explore the coordinated interaction of translational and transcriptional programs of human cellular senescence. We find that …
Localization and function of multivesicular-bodies that …
WebApr 11, 2024 · Parkinson's disease (PD) is a neurodegenerative disease with both genetic and sporadic origins. In this study, we investigated the electrophysiological properties, synaptic activity, and gene expression differences in dopaminergic (DA) neurons derived from induced pluripotent stem cells (iPSCs) of healthy controls, sporadic PD (sPD) … WebMar 20, 2024 · Aging is a highly complex process associated with numerous changes at the organismal, tissue, cellular and molecular levels, characterized by dysregulation of different physiological systems (such as the immune, central and peripheral nervous, endocrine, metabolic and other systems) from their optimal homeostatic state (Xu and Larbi 2024; … d g software
Glucotypes reveal new patterns of glucose dysregulation
WebApr 14, 2024 · A recent article by Mensah et al. looks at a rare genetic disease to identify a frameshift mutation, which triggered aberrant phase separation and nucleolar … WebOct 9, 2016 · It is currently well recognized that microRNA deregulation is an hallmark of human cancer, and how an aberrant expression of these tiny regulatory RNA molecules in several cell types is not just a random association, but it plays a causal role in different steps of the tumorigenic process, from the initiation and development to progression toward … WebJan 24, 2024 · Dysregulation of the tumor suppressor TP53 is important in the pathogenesis of many cancers, including MM. In newly-diagnosed MM patients, TP53 … dgsom housing offers calendar