Cytoskeleton-associated protein 4
WebOct 31, 2012 · Cytoskeleton-associated protein 4 (CKAP4; also known as p63, CLIMP-63, or ERGIC-63) is a 63 kDa, reversibly palmitoylated and phosphorylated, type II transmembrane (TM) protein, originally identified as a resident of the endoplasmic reticulum (ER)/Golgi intermediate compartment (ERGIC). WebWhat Is the Cytoskeleton Made Of? The cytoskeleton of eukaryotic cells is made of filamentous proteins, and it provides mechanical support to the cell and its cytoplasmic constituents. All...
Cytoskeleton-associated protein 4
Did you know?
WebAug 21, 2024 · The cytoskeleton is a network of fibers forming the "infrastructure" of eukaryotic cells, prokaryotic cells, and archaeans. In eukaryotic cells, these fibers consist of a complex mesh of protein … WebJun 1, 2024 · CKAP4 is a 63-kDa non-glycosylated and reversibly palmitoylated type II transmembrane protein that has been shown to anchor rough endoplasmic reticulum and microtubules in epithelial cells.5 Although CKAP4 was described as an endoplasmic reticulum–resident protein, it is also now known to be expressed on the surface of …
WebJan 31, 2024 · Cytoskeleton-associated protein 4 is a novel marker for activated fibroblasts that positively correlates with known myofibroblast markers in both … WebFeb 22, 2014 · Cytoskeleton-associated membrane protein 4 (CKAP4), also known as P63, with a molecular weight 63 kilodaltons, is a type of type II transmembrane protein …
WebApr 7, 2015 · cytoskeleton-linking membrane protein (CLIMP-63)/ cytoskeleton-associated protein 4 (CKAP4), palmitoyl-acyltransferase 2 (has a DHHC motif) [DHHC2], endoplasmic reticulum (ER) cytoskeleton anchor, nuclear translocation, palmitoylation, plasma membrane receptor, rough endoplasmic reticulum (RER) WebSep 2, 2024 · CKAP4 expression is associated with tumor grade in gliomas. Quantification of CKAP4 expression using RNA sequencing data from A GEPIA and B CGGA …
WebSep 22, 2024 · Here, we find cytoskeleton-associated protein 4 (CKAP4) is a novel receptor for Spike protein invasion, as evidenced by its specific interaction with Spike …
impact of holding music festivalWebJan 8, 2024 · cytoskeleton-associated protein 4, 63 kDa membrane protein, 63-kDa cytoskeleton-linking membrane protein GeneRIFs: Gene References Into Functions … impact of hiv stigmaWebCytoskeleton-associated protein 4 (CKAP4) is also known as p63 and cytoskeleton-linking membrane protein 63kDa (CLIMP-63). It was first described as a palmitoylated single-pass transmembrane receptor that localized to the rough endoplasmic reticulum as well as the cell membrane. impact of homework on studentsWebProtein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin - actin interaction. Protein 4.1 (80 kD) interacts with spectrin and short actin filaments to form the erythrocyte membrane skeleton. impact of hiv/aids on healthWebOct 31, 2012 · Abstract and Figures. Cytoskeleton-associated protein 4 (CKAP4; also known as p63, CLIMP-63, or ERGIC-63) is a 63 kDa, reversibly palmitoylated and … impact of homelessness on mental healthWebJan 8, 2024 · Suggest a role for cytoskeleton-associated protein 4 in modulating fibroblast activation in the injured heart. CLIMP-63 (also known as CKAP4), is the partner of triadin, is responsible for this association of triads and microtubules. p63 positively regulates desmosome adhesion by directly controlling the expression of several desmosome genes ... impact of home learning environmentWebMay 17, 2024 · CKAP4 (cytoskeleton‐associated protein 4) is a DKK1 binding protein expressed on the surface of cells, with DKK1/CKAP4 promoting pancreatic cancer and lung cancer . DKK1 is considered a factor that can modulate the β‐catenin pathway and stimulate cancer cells or noncancerous proliferation [61, 62]. Zyxin localizes to focal adhesion sites ... impact of homelessness in ireland