Ctgf antibodies

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August undefined, 2024

WebThe multimodular CTGF has the ability to bind multiple ligands and has numerous effects on development, differentation, and disease. The C-terminal cysteine knot motif contains the HSPG (proteoglycan) and low …

CTGF is a central mediator of tissue remodeling and fibrosis and …

WebJun 13, 2024 · Our data indicate that inhibition of CTGF signaling presents an attractive therapeutic approach in SSc. Anti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosis ... (KO)) or a human anti-CTGF monoclonal antibody, FG-3019. Methods: Angiotensin II … WebCTGF is a heparin-binding pleiotropic growth factor involved in chondrogenesis and potentially skeletogenesis. CTGF promotes the adhesion of epithelial cells and fibroblasts, stimulates integrin … high-pressure mass spectrometry hpms

CTGF - Wikipedia

WebTarget Information. Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. WebThis affinity purified antibody,in conjunction with Biotinylated antibody Human CTGF (AP01150BT) as a detectionantibody, allows the detection of at least 0.2-0.4 ng/well of recombinant Human CTGF. Western blot: To detect Human CTGF this antibody can be used at a concentration of0.1-0.2 μg/mL. WebMar 18, 2024 · CTGF Antibody (L-20): sc-14939. 4.7 (15) Write a review Ask a question. CTGF Antibody (L-20) is a goat polyclonal IgG; 100 µg/ml. epitope mapping within an internal region of CTGF of human origin. Discontinued polyclonal antibody. See … high-powered field

CTGF Polyclonal Antibody (PA5-32193) - Thermo Fisher Scientific

WebApr 12, 2024 · The coverslips were incubated with primary antibodies against USP1 (Cell Signaling Technology, Cat# 8033, 1:200) and TAZ (Abcam, ab224239, 1:200) at 4 °C overnight. WebConnective tissue growth factor (CTGF) is a novel cysteine-rich, secreted protein. Recently, we found that inhibition of the endogenous expression of CTGF by its antisense oligonucleotide and antisense RNA suppresses the proliferation and migration of vascular endothelial cells. In the present study … high-pressure research in mineral physicsWebCTGF Antibody detects endogenous levels of total CTGF. RRID: AB_2843901 Cite Format: Affinity Biosciences Cat# AF7537, RRID:AB_2843901. Conjugate: Unconjugated. Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific). Storage: ... small letter flash cards

"WebThis antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human CTGF (500-P252Bt) as a detection antibody, allows the detection of at least 0.2 … " - Ctgf antibodies

Ctgf antibodies

WebJun 1, 2024 · Antibody. As CTGF is a secreted protein, monoclonal antibodies are an option as blockade agents. The most advanced trials are of treatment with FG-3019/pamrevlumab, a humanized anti-CTGF antibody, which has been tested in the clinic for muscular dystrophy, pancreatic cancer, liver fibrosis, idiopathic pulmonary fibrosis, … WebRecombinant Mouse CTGF Protein expressed from Escherichia coli (E. coli). Conjugated to His tag.Order Protein ABIN7122479 online. ... Comparison List Basket Phone: +1 877 …

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WebCTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN … WebCTGF/CCN2 was detected in immersion fixed paraffin-embedded sections of human kidney array using Goat Anti-Human CTGF/CCN2 C-Terminus …

WebAntibodies that detect CTGF can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and … WebAnti-CTGF antibody [EPR20728] (ab209780) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – …

WebApr 13, 2024 · The identification of tissue-specific promoters for gene therapeutic constructs is one of the aims of complex tumor therapy. The genes encoding the fibroblast activation protein (FAP) and the connective tissue growth factor (CTGF) can function in tumor-associated stromal cells but are practically inactive in normal adult cells. Accordingly, the … WebCTGF, also known as CCN2, is a member of the CCN family of matricellular proteins. CTGF, a cysteine-rich, matrix-associated, heparin-binding protein, is widely expressed in various human tissues and organs. CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal ...

WebAnti-CTGF antibody Specifications. Our Abpromise guarantee covers the use of ab50044 in the following tested applications. The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. Applications. SDS-PAGE. Functional Studies. Form. Lyophilized ...

WebThis affinity purified antibody,in conjunction with Biotinylated antibody Human CTGF (AP01150BT) as a detectionantibody, allows the detection of at least 0.2-0.4 ng/well of … high-priced 意味WebMar 22, 2024 · CTGF Antibody (E-5) is available as both the non-conjugated anti-CTGF antibody form, as well as multiple conjugated forms of anti-CTGF antibody, including … small leprechaun clip artWebConnective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial … high-priced spread crosswordWebJun 6, 2012 · CTGF is a secreted matricellular protein with very complex biology. It has been shown to modulate many signaling pathways leading to cell adhesion and migration, angiogenesis, myofibroblast activation, and extracellular matrix deposition and remodeling, which together lead to tissue remodeling and fibrosis. It has been reported in the … small letter cursive alphabetsWebCTGF, also known as CCN2 or connective tissue growth factor, is a member of the CCN family of matricellular proteins. CTGF, a cysteine-rich, matrix-associated, heparin-binding protein, is widely expressed in various … high-profile disposable blades 818WebOct 26, 2024 · Connective tissue growth factor (CTGF)-induced angiogenesis is a crucial factor in rheumatoid arthritis (RA), but CTGF-interacting protein and related molecular mechanism of their interaction have not been fully elucidated. CTGF-interacting proteins were identified through the LC-MS/MS analysis of the Co-IP products from fibroblast-like … high-priced recyclingWebMar 10, 2024 · Connective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN protein family of secreted proteins with roles in diverse biological processes. … small letter head